Reference Dose (RfD), Eliciting Dose (ED) and Action Level Calculator

ED and Action Level Calculator

Estimation by interpolation between tabulated ED values and Action Level calculation.

FAO/WHO-Codex reference

Interpretation:

Select an allergen and enter the values.

X-axis is shown on a logarithmic scale. The curve is built directly by interpolation between tabulated points, without fitting a global mathematical function.

Sources and calculation method

Full ED dataset: Houben GF, Baumert JL, Blom WM, Kruizinga AG, Meima MY, Remington BC, Wheeler MW, Westerhout J, Taylor SL. Full range of population Eliciting Dose values for 14 priority allergenic foods and recommendations for use in risk characterization. Food Chem Toxicol. 2020 Dec;146:111831. doi: 10.1016/j.fct.2020.111831.

Official Reference Doses: FAO/WHO-Codex values expressed as mg total protein from the allergenic source.

ED to dose: the dose corresponding to the selected ED is interpolated using the two closest tabulated ED values.

Dose to ED: the ED corresponding to the consumed dose is interpolated using the two closest tabulated dose values.

Action Level: Reference dose (mg protein) / Portion (g) × 1000, expressed as mg allergenic protein/kg food.